Use chlorhexidine digluconate effectively kill Enterococcus faecalis in endodontic biofilm
发布时间：2016-05-27
Nonequilibrium plasma has been reported to effectively kill Enterococcus faecalis in endodontic biofilm compared with chlorhexidine digluconate (CHX). The purpose of this study was to evaluate the antimicrobial in vitro activity of modified nonequilibrium plasma with CHX against E. faecalis and multispecies biofilms on bovine dentin discs.
Sterile bovine dentin discs were incubated with E. faecalis or a mixture of bacteria from human dental root canal infections to form 1- and 3-week-old biofilms. The specimens were subjected to nonequilibrium plasma, modified nonequilibrium plasma with chlorhexidine digluconate, and 2% CHX for 2- and 5-minute exposure. After treatment, the biofilms were stained with viability dyes and examined by confocal laser scanning microscopy and 3-dimensional reconstruction analysis. The proportions of bacterial cells killed by the treatments were calculated.
Comparison of two disinfectant used for skin disinfection PICC maintenance. Methods: 208 cases were randomly divided into experimental and control groups, respectively chlorhexidine digluconate disinfectant and povidone-iodine for disinfection, two groups were observed catheter infection maintenance costs, maintenance time difference of results through clinical practice, the two groups have no significant difference in the incidence of catheter infection, but the experimental group has lower maintenance costs and maintenance time. Conclusion: chlorhexidine gluconate disinfecting was compared with povidone-iodine, can play a preventive catheter complications, and can significantly reduce maintenance costs and improve clinical efficiency.
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