Objective: The aim of this study was to compare early wound healing, tooth staining and patient acceptance with two different post-surgical maintenance protocols. Materials and methods: Forty patients scheduled for flap surgery to treat periodontal pockets or accommodate dental implants were randomly assigned to receive the following two different post-surgical maintenance protocols: (a) 2 weeks rinsing with a 0.05 % chlorhexidine digluconate (CHX)/herbal extract combination (test) or (b) a 0.1 % Chlorhexidine digluconate (CHX) solution (control). Early wound healing was evaluated clinically and immunologically. Tooth staining and patient acceptance were assessed by means of visual analogue scale (VAS).
Results of the experiment of Chlorhexidine digluconate: Both groups presented with comparable wound healing profiles. No statistically significant differences were observed between the two protocols regarding early wound healing and plaque index (p > 0.05). However, in the control group, statistically significantly more patients felt discomfort due to tooth staining (p = 0.0467). Compared with patients from the test group, patients in the control group reported statistically significant more irritation of taste at week 1 (p = 0.0359) and at week 2 (p = 0.0042).
Something about Chlorhexidine digluconate: Chlorhexidine hydrochloride. White or almost white crystalline powder; odorless, bitter taste. Very slightly soluble in water, slightly soluble in ethanol, slightly soluble in propylene glycol. For the disinfection of preservatives, their broad and strong antibacterial sterilization effect on Gram-positive antibacterial effect is stronger than Yin Yin is negative, than the quaternary ammonium salt cationic surfactant is a strong, effective on fungi, but acid-fast bacteria , spores and viruses invalid. In serum, the presence of blood is still valid. Non-irritating to the organization. For skin disinfection, wash and disinfect the wound and soaking surgical instruments.
Chlorhexidine acetate. White or almost white crystalline powder; Cymbalta cationic surfactants preservatives, antibacterial spectrum, strong antibacterial activity characteristics. Its mechanism of action is to change the permeability of the bacterial cell membrane. But spores, viruses and bacteria acid invalid. For the disinfection antiseptic drugs, it has a very strong broad-spectrum antimicrobial, bactericidal effect on Gram-positive bacteria and gram-negative bacteria are effective. For hand, equipment, wound and skin disinfection. Chlorhexidine gluconate. Colorless liquid, odorless or almost odorless. Miscible with water, soluble in ethanol and acetone. Application: disinfection antiseptic medicine.