Sample of Chlorhexidine Products for Healthcare Use

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In our never-ending attempt to vanquish healthcare-associated infections, the latest weapon to emerge is chlorhexidine gluconate (CHG). Not that CHG is exactly new: as an antiseptic, it has been around for more than 50 years.^[¹^]Initially a topical disinfectant, CHG has recently crept into numerous other products and devices. We now have not only skin antiseptic solutions but surgical scrub products, bathing cloths, oral rinses, intravenous catheters, topical dressings, and implantable surgical mesh -- all infused with this relatively safe, broad-spectrum antiseptic (Table). Nor is the use of CHG limited to the hospital: CHG is increasingly added as a preservative to cosmetics and other personal care products.

Sample of Chlorhexidine Products for Healthcare Use

Product	Format	CHG Concentration	Healthcare Uses
Topical solution	Sponge applicators Swab sticks Ampules	2% or 3.15% With 70% isopropyl alcohol	Skin preparation for surgery, invasive procedures, central lines to prevent SSI and BSI
Scrub solution	Liquid detergent (sudsing base)	2% or 4% aqueous	Preoperative showering/bathing General skin cleansing
Washcloth	Impregnated single-use washcloth/wipe	2% aqueous	Daily bathing in ICU patients
Dental solution	Oral rinse	0.12%	Decontaminate oral cavity (ventilator-associated pneumonia prevention protocols)
Gauze dressing	Cotton-weave gauze dressing	0.5% with paraffin	Wounds or burns
Catheter dressing	CHG pad or integrated with semi-permeable transparent dressing	2% gel pad or foam disk	Peripherally inserted central catheters Central line dressings
Hand rub	Waterless antiseptic hand gel	1% alcohol based with emollients	Hand sanitizer for healthcare personnel (nonsoiled hands)

BSI = bloodstream infection; CHG = chlorhexidine gluconate; ICU = intensive care unit; SSI = surgical site infection

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